Vaccine Induced Liver Injury/ Hepatitis, Myth or Fact? Peer Reviewed Case Report

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In late April 2022, a new peer-reviewed case report was published in the Journal of Hepatology titled, SARS-CoV-2 vaccine can elicit a CD8 T-cell dominant hepatitis.

This is a very reputable journal for liver-related studies. This study appeared to have presented a compelling case showing the Pfizer mRNA vaccine induced a different type of autoimmune hepatitis or inflammation of the liver that was caused by CD 8 cytotoxic T cells.

Let’s take a look together!


Disclaimer: This video is Dr. Hong’s interpretation and summary of publically available scientific information This video is not intended to serve as any advice regarding the treatment, prevention, and diagnosis of any diseases Dr. Hong has no connections and receives no monetary compensation from any pharmaceutical companies and government. This video is for educational purposes only.

To learn more: Immunology Short and Brief Series https://youtube.com/playlist?list=PLk…

Source References: Autoimmune Hepatitis-Like Syndrome Following COVID-19 Vaccination: A Systematic Review of the Literature https://link.springer.com/article/10….

An unusual case of acute cholestatic hepatitis after m-RNABNT162b2 (Comirnaty) SARS-CoV-2 vaccine: Coincidence, autoimmunity or drug-related liver injury: https://www.journal-of-hepatology.eu/article/S0168-8278(21)01904-8/fulltext

Liver injury following SARS-CoV-2 vaccination: A multicenter case series https://www.journal-of-hepatology.eu/…

Letter to the editor: Exacerbation of autoimmune hepatitis after COVID-19 vaccination https://aasldpubs.onlinelibrary.wiley…

Autoimmune Hepatitis-Like Syndrome Following COVID-19 Vaccination: Real or Imagined? https://link.springer.com/article/10….

SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis https://www.journal-of-hepatology.eu/…

Epidemiology of Autoimmune Hepatitis (AIH) in the United States Between 2014 and 2019: A Population-based National Study https://pubmed.ncbi.nlm.nih.gov/33074…

Autoimmune Hepatitis https://rarediseases.org/rare-disease…

Liver Function Tests – Mayoclinic https://www.mayoclinic.org/tests-proc…

Liver injury in COVID-19: clinical features and treatment management https://virologyj.biomedcentral.com/a…

Cardiac Injury in COVID-19: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/33656…

Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave https://www.nature.com/articles/s4159…