The Downslope of the Omicron Surge, and What to Do as We Turn the Corner


In this Covid Grand Rounds, we’ll begin with a George Rutherford update on the state of the pandemic – are we truly leaving the January Omicron surge? Is there any indication of backsliding? Should we be concerned about the Omicron sub-variant BA.2?

Following that, we’ll add Sarah Doernberg and Peter Chin-Hong to the conversation, posing a number of scenarios and soliciting their recommendations about masking, testing, boosters, and therapies. For example, if cases continue to fall, do I need to mask in the supermarket? Do kids need to mask in schools? How should I use home antigen testing? Does a person with two mRNA shots and a breakthrough infection still need a booster? Does anybody need a fourth shot? And which outpatients should get Paxlovid? Monoclonal antibodies? Remdesivir? And are any of them available?


George Rutherford, MD, Professor, Dept. of Epidemiology & Biostatistics; Director of the Prevention and Public Health Group.

Peter Chin-Hong, MD, Professor of Medicine, Division of Infectious Diseases at UCSF Health.

Sarah Doernberg, MD, Associate Professor, Division of Infectious Diseases at UCSF Health; Medical Director, Adult Antimicrobial Stewardship at UCSF Medical Center.

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